anx_I__cpt_22__cpt_1__cpt_1__text_5

In the Union, cardiovascular disease annually accounts for more than 2 million deaths and costs the economy more than EUR 192 billion while cancer accounts for a quarter of all deaths and is the number one cause of death for people aged 45-64. Over 27 million people in the Union suffer from diabetes and over 120 million from rheumatic and musculoskeletal conditions. Rare diseases remain a major challenge, affecting approximately 30 million people across Europe. The total cost of brain disorders (including, but not limited to those affecting mental health, including depression) has been estimated at EUR 800 billion. It is estimated that mental disorders alone affect 165 million people in the Union, at a cost of EUR 118 billion. These sums are expected to rise significantly, largely as a result of Europe's ageing population and the associated increases in neurodegenerative diseases. Environmental, occupational, life-style and socio-economic factors are relevant in several of these conditions with up to one third of the global disease burden estimated to be related to these.

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Source: EUR-Lex (Cellar) · retrieved 2026-11-03 · Text as adopted (Official Journal); later amendments are not incorporated in this text.