Test Methods

A HP 11 assessment of a waste is to be made on the basis of: — the identification of the individual substances in the waste; — their classification; — reference to concentration limits. If testing is considered to determining this hazard property, waste containing substances listed in Table 19 should be assessed for mutagenic properties in accordance with the ECHA CLP Guidance. Part B of the Annex to the Test Methods Regulation provides the following in-vitro test methods which may be considered in the assessment of HP 11 ‘Mutagenic’: — B.10. Mutagenicity — In Vitro Mammalian Chromosome Aberration Test — B.13/14. Mutagenicity: Reverse Mutation Test Using Bacteria (31) — B.15. Mutagenicity Testing and Screening for Carcinogenicity Gene Mutation — Saccharomyces Cerevisiae — B.17. Mutagenicity — In Vitro Mammalian Cell Gene Mutation Test Test methods given in the Test Methods Regulation that rely on animal testing are not appropriate (32).

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Source: EUR-Lex (Cellar) · retrieved 2026-09-07