Test Methods

A HP 4 assessment of a waste is to be done on the basis of — identification of the individual substances in the waste; — their classification; — reference to concentration limits in Annex III to the WFD. If testing is considered to determine this hazard property, waste containing substances listed in Table 12 should be tested for irritant properties in accordance with the ECHA CLP Guidance. A mixture assigned H315, H318 or H319 by this assessment is considered HP 4. If testing is considered, a combination of acid/ alkali reserve test and in-vitro testing is recommended. An example on how to integrate the acid/ alkali reserve and in-vitro testing into a general testing setting can be found in the UK Guidance. As already described above, the acid/ alkali reserve test measures the buffering capacity of the waste. Part B of the Annex to the Test Methods Regulation provides the following test method which may be regarded in the assessment of HP 4 ‘Irritant’: — B.46 In Vitro Skin Irritation: Reconstructed Human Epidermis Test Method Test methods given in the Test Methods Regulation that rely on animal testing are not appropriate (11). Further in-vitro methods may be available from other sources, such as the European Union Reference Laboratory for alternatives to animal testing (12). Where a hazardous property of a waste has been assessed by a test and by using the concentrations of hazardous substances as indicated in Annex III to the WFD, the results of the test should prevail.

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Source: EUR-Lex (Cellar) · retrieved 2026-09-07